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CAS 89778-27-8 White Powder Low Estrogen Steroids Toremifene Citrate / Fareston

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CAS 89778-27-8 White Powder Low Estrogen Steroids Toremifene Citrate / FarestonQuick details Product Name: Toremifene Citrate Synonyms: Fareston CAS Registry Number: 89778-27-8 Assay: 99% Molecular Formula: C26H28ClNO.C6H8O7 Molecular Weight: 598.09 Melting Point: 158-164 ºC Boiling Point: 535.1 ºC at 760 mmHg Density: 1.045g/cm3 Refractive index: 1,416-1,418 Appearance: White or almost white powder Toremifene Citrate EffectToremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene. It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a ‘fake’ Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially ‘tricks’ the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels. Toremifene Citrate exerts its effects by antagonizing the estrogen receptor in some tissues, and agonizing it in others. In this way, certain estrogenic pathways are activated and others are blockaded. It seems to exert estrogenic effects"height:190px; max-width:650px; width:650px" /

  • Purchase Type:  
  • Quantity:  1+
  • Packaging:  Negotiable
  • Place of Origin:  China
  • PriceTerms:  Negotiable
  • Delivery Lead Time:  
  • Information validity to:  2017-2-16
  • Contact Preference:  Intended person ask phone connection.

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